3byz

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Image:3byz.png

Template:STRUCTURE 3byz

2-Amino-1,3-thiazol-4(5H)-ones as Potent and Selective 11-Hydroxysteroid Dehydrogenase Type 1 Inhibitors

Template:ABSTRACT PUBMED 18419108

About this Structure

3BYZ is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

2-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 mice., Johansson L, Fotsch C, Bartberger MD, Castro VM, Chen M, Emery M, Gustafsson S, Hale C, Hickman D, Homan E, Jordan SR, Komorowski R, Li A, McRae K, Moniz G, Matsumoto G, Orihuela C, Palm G, Veniant M, Wang M, Williams M, Zhang J, J Med Chem. 2008 May 22;51(10):2933-43. Epub 2008 Apr 18. PMID:18419108

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