2hg4

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Image:2hg4.png

Template:STRUCTURE 2hg4

Structure of the ketosynthase-acyltransferase didomain of module 5 from DEBS.

Template:ABSTRACT PUBMED 16844787

About this Structure

2HG4 is a Single protein structure of sequence from Saccharopolyspora erythraea. Full crystallographic information is available from OCA.

Reference

The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase., Tang Y, Kim CY, Mathews II, Cane DE, Khosla C, Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11124-9. Epub 2006 Jul 14. PMID:16844787

Reconstituting modular activity from separated domains of 6-deoxyerythronolide B synthase., Kim CY, Alekseyev VY, Chen AY, Tang Y, Cane DE, Khosla C, Biochemistry. 2004 Nov 9;43(44):13892-8. PMID:15518537

Harnessing the biosynthetic code: combinations, permutations, and mutations., Cane DE, Walsh CT, Khosla C, Science. 1998 Oct 2;282(5386):63-8. PMID:9756477

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