1pv8

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Template:STRUCTURE 1pv8

Contents

Crystal structure of a low activity F12L mutant of human phorphobilinogen synthase

Template:ABSTRACT PUBMED 12897770

Disease

Known disease associated with this structure: Porphyria, acute hepatic OMIM:[125270], Lead poisoning, susceptibility to OMIM:[125270]

About this Structure

1PV8 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Control of tetrapyrrole biosynthesis by alternate quaternary forms of porphobilinogen synthase., Breinig S, Kervinen J, Stith L, Wasson AS, Fairman R, Wlodawer A, Zdanov A, Jaffe EK, Nat Struct Biol. 2003 Sep;10(9):757-63. Epub 2003 Aug 3. PMID:12897770

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