2qhm

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Template:STRUCTURE 2qhm

crystal structure of Chek1 in complex with inhibitor 2a

Template:ABSTRACT PUBMED 17804227

About this Structure

2QHM is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Optimization of a pyrazoloquinolinone class of Chk1 kinase inhibitors., Brnardic EJ, Garbaccio RM, Fraley ME, Tasber ES, Steen JT, Arrington KL, Dudkin VY, Hartman GD, Stirdivant SM, Drakas BA, Rickert K, Walsh ES, Hamilton K, Buser CA, Hardwick J, Tao W, Beck SC, Mao X, Lobell RB, Sepp-Lorenzino L, Yan Y, Ikuta M, Munshi SK, Kuo LC, Kreatsoulas C, Bioorg Med Chem Lett. 2007 Nov 1;17(21):5989-94. Epub 2007 Aug 19. PMID:17804227

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