3caj

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Template:STRUCTURE 3caj

Crystal structure of the human carbonic anhydrase II in complex with ethoxzolamide

Template:ABSTRACT PUBMED 18359629

About this Structure

3CAJ is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Carbonic anhydrase inhibitors: The X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitors., Di Fiore A, Pedone C, Antel J, Waldeck H, Witte A, Wurl M, Scozzafava A, Supuran CT, De Simone G, Bioorg Med Chem Lett. 2008 Mar 18;. PMID:18359629

Positions of His-64 and a bound water in human carbonic anhydrase II upon binding three structurally related inhibitors., Smith GM, Alexander RS, Christianson DW, McKeever BM, Ponticello GS, Springer JP, Randall WC, Baldwin JJ, Habecker CN, Protein Sci. 1994 Jan;3(1):118-25. PMID:8142888

Structures of murine carbonic anhydrase IV and human carbonic anhydrase II complexed with brinzolamide: molecular basis of isozyme-drug discrimination., Stams T, Chen Y, Boriack-Sjodin PA, Hurt JD, Liao J, May JA, Dean T, Laipis P, Silverman DN, Christianson DW, Protein Sci. 1998 Mar;7(3):556-63. PMID:9541386

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