2ien
From Proteopedia
Crystal structure analysis of HIV-1 protease with a potent non-peptide inhibitor (UIC-94017)
Template:ABSTRACT PUBMED 15066436
About this Structure
2IEN is a Single protein structure of sequence from Human immunodeficiency virus 1. This structure supersedes the now removed PDB entry 1s6g. Full crystallographic information is available from OCA.
Reference
High resolution crystal structures of HIV-1 protease with a potent non-peptide inhibitor (UIC-94017) active against multi-drug-resistant clinical strains., Tie Y, Boross PI, Wang YF, Gaddis L, Hussain AK, Leshchenko S, Ghosh AK, Louis JM, Harrison RW, Weber IT, J Mol Biol. 2004 Apr 23;338(2):341-52. PMID:15066436
Novel bis-tetrahydrofuranylurethane-containing nonpeptidic protease inhibitor (PI) UIC-94017 (TMC114) with potent activity against multi-PI-resistant human immunodeficiency virus in vitro., Koh Y, Nakata H, Maeda K, Ogata H, Bilcer G, Devasamudram T, Kincaid JF, Boross P, Wang YF, Tie Y, Volarath P, Gaddis L, Harrison RW, Weber IT, Ghosh AK, Mitsuya H, Antimicrob Agents Chemother. 2003 Oct;47(10):3123-9. PMID:14506019
Page seeded by OCA on Mon Jul 28 08:36:36 2008
Categories: HIV-1 retropepsin | Human immunodeficiency virus 1 | Single protein | Boross, P I. | Gaddis, L. | Ghosh, A K. | Harrison, R W. | Hussain, A K. | Leshchenko, S. | Louis, J M. | Manna, D. | Tie, Y. | Wang, Y F. | Weber, I T. | Darunavir | Dimer | Hiv-1 protease | Inhibitor | Tmc114 | Uic-94017
