1z8g

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Template:STRUCTURE 1z8g

Crystal structure of the extracellular region of the transmembrane serine protease hepsin with covalently bound preferred substrate.

Template:ABSTRACT PUBMED 15839837

About this Structure

1Z8G is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers., Herter S, Piper DE, Aaron W, Gabriele T, Cutler G, Cao P, Bhatt AS, Choe Y, Craik CS, Walker N, Meininger D, Hoey T, Austin RJ, Biochem J. 2005 Aug 15;390(Pt 1):125-36. PMID:15839837

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