1zsa

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Template:STRUCTURE 1zsa

Contents

CARBONIC ANHYDRASE II MUTANT E117Q, APO FORM

Template:ABSTRACT PUBMED 8639494

Disease

Known disease associated with this structure: Osteopetrosis, autosomal recessive 3, with renal tubular acidosis OMIM:[611492]

About this Structure

1ZSA is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Reversal of the hydrogen bond to zinc ligand histidine-119 dramatically diminishes catalysis and enhances metal equilibration kinetics in carbonic anhydrase II., Huang, CC, Lesburg CA, Kiefer LL, Fierke CA, Christianson DW, Biochemistry. 1996 Mar 19;35(11):3439-46. PMID:8639494

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