1ze8

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Template:STRUCTURE 1ze8

Carbonic anhydrase II in complex with a membrane-impermeant sulfonamide inhibitor

Template:ABSTRACT PUBMED 16134940

About this Structure

1ZE8 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Carbonic anhydrase inhibitors: stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme II., Menchise V, De Simone G, Alterio V, Di Fiore A, Pedone C, Scozzafava A, Supuran CT, J Med Chem. 2005 Sep 8;48(18):5721-7. PMID:16134940

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