1hvy
From Proteopedia
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| 1hvy, resolution 1.90Å () | |||||||||
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| Ligands: | , , | ||||||||
| Non-Standard Residues: | |||||||||
| Activity: | Thymidylate synthase, with EC number 2.1.1.45 | ||||||||
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| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Human thymidylate synthase complexed with dUMP and Raltitrexed, an antifolate drug, is in the closed conformation
Template:ABSTRACT PUBMED 11329255
About this Structure
1HVY is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Human thymidylate synthase is in the closed conformation when complexed with dUMP and raltitrexed, an antifolate drug., Phan J, Koli S, Minor W, Dunlap RB, Berger SH, Lebioda L, Biochemistry. 2001 Feb 20;40(7):1897-902. PMID:11329255
Page seeded by OCA on Tue Jul 1 08:53:49 2008
