1mu6
From Proteopedia
Crystal Structure of Thrombin in Complex with L-378,622
Template:ABSTRACT PUBMED 12570369
About this Structure
1MU6 is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Metabolism-directed optimization of 3-aminopyrazinone acetamide thrombin inhibitors. Development of an orally bioavailable series containing P1 and P3 pyridines., Burgey CS, Robinson KA, Lyle TA, Sanderson PE, Lewis SD, Lucas BJ, Krueger JA, Singh R, Miller-Stein C, White RB, Wong B, Lyle EA, Williams PD, Coburn CA, Dorsey BD, Barrow JC, Stranieri MT, Holahan MA, Sitko GR, Cook JJ, McMasters DR, McDonough CM, Sanders WM, Wallace AA, Clayton FC, Bohn D, Leonard YM, Detwiler TJ Jr, Lynch JJ Jr, Yan Y, Chen Z, Kuo L, Gardell SJ, Shafer JA, Vacca JP, J Med Chem. 2003 Feb 13;46(4):461-73. PMID:12570369
Page seeded by OCA on Mon Jul 28 14:59:56 2008
Categories: Homo sapiens | Protein complex | Thrombin | Barrow, J C. | Bohn, D. | Burgey, C S. | Chen, Z. | Clayton, F C. | Coburn, C A. | Cook, J J. | Dorsey, B D. | Gardell, S J. | Holahan, M A. | Jr., J J.Lynch. | Jr., T J.Detwiler. | Krueger, J A. | Kuo, L. | Leonard, Y M. | Lewis, S D. | Lucas, B J. | Lyle, E A. | Lyle, T A. | McDonough, C M. | McMasters, D R. | Miller-Stein, C. | Robinson, K A. | Sanders, W M. | Sanderson, P E. | Shafer, J A. | Singh, R. | Sitko, G R. | Stranieri, M T. | Vacca, J P.J. | Wallace, A A. | White, R B. | Williams, P D. | Wong, B. | Yan, Y. | Blood clotting | Hydrolase
