2isp

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Template:STRUCTURE 2isp

Ternary complex of DNA Polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-methylene triphosphate

Template:ABSTRACT PUBMED 17209556

About this Structure

2ISP is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Modifying the beta,gamma leaving-group bridging oxygen alters nucleotide incorporation efficiency, fidelity, and the catalytic mechanism of DNA polymerase beta., Sucato CA, Upton TG, Kashemirov BA, Batra VK, Martinek V, Xiang Y, Beard WA, Pedersen LC, Wilson SH, McKenna CE, Florian J, Warshel A, Goodman MF, Biochemistry. 2007 Jan 16;46(2):461-71. PMID:17209556

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