2r3q
From Proteopedia
Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor
Template:ABSTRACT PUBMED 17937404
About this Structure
2R3Q is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Structure-guided discovery of cyclin-dependent kinase inhibitors., Fischmann TO, Hruza A, Duca JS, Ramanathan L, Mayhood T, Windsor WT, Le HV, Guzi TJ, Dwyer MP, Paruch K, Doll RJ, Lees E, Parry D, Seghezzi W, Madison V, Biopolymers. 2007 Oct 15;. PMID:17937404
Versatile templates for the development of novel kinase inhibitors: Discovery of novel CDK inhibitors., Dwyer MP, Paruch K, Alvarez C, Doll RJ, Keertikar K, Duca J, Fischmann TO, Hruza A, Madison V, Lees E, Parry D, Seghezzi W, Sgambellone N, Shanahan F, Wiswell D, Guzi TJ, Bioorg Med Chem Lett. 2007 Nov 15;17(22):6216-9. Epub 2007 Sep 8. PMID:17904366
Page seeded by OCA on Mon Jul 28 19:17:35 2008
Categories: Cyclin-dependent kinase | Homo sapiens | Single protein | Duca, J S. | Fischmann, T O. | Hruza, A W. | Madison, V M. | Atp-binding | Cancer | Cell cycle | Cell division | Inhibition | Mitosis | Nucleotide-binding | Phosphorylation | Polymorphism | Serine/threonine-protein kinase | Transferase