1z5m
From Proteopedia
Crystal Structure Of N1-[3-[[5-bromo-2-[[3-[(1-pyrrolidinylcarbonyl)amino]phenyl]amino]-4-pyrimidinyl]amino]propyl]-2,2-dimethylpropanediamide Complexed with Human PDK1
Template:ABSTRACT PUBMED 15772071
About this Structure
1Z5M is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Novel small molecule inhibitors of 3-phosphoinositide-dependent kinase-1., Feldman RI, Wu JM, Polokoff MA, Kochanny MJ, Dinter H, Zhu D, Biroc SL, Alicke B, Bryant J, Yuan S, Buckman BO, Lentz D, Ferrer M, Whitlow M, Adler M, Finster S, Chang Z, Arnaiz DO, J Biol Chem. 2005 May 20;280(20):19867-74. Epub 2005 Mar 16. PMID:15772071
High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site., Biondi RM, Komander D, Thomas CC, Lizcano JM, Deak M, Alessi DR, van Aalten DM, EMBO J. 2002 Aug 15;21(16):4219-28. PMID:12169624
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