1pzl

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Template:STRUCTURE 1pzl

Contents

Crystal structure of HNF4a LBD in complex with the ligand and the coactivator SRC-1 peptide

Template:ABSTRACT PUBMED 14982928

Disease

Known disease associated with this structure: MODY, type I OMIM:[600281], Diabetes mellitus, noninsulin-dependent OMIM:[600281]

About this Structure

1PZL is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Structural basis for HNF-4alpha activation by ligand and coactivator binding., Duda K, Chi YI, Shoelson SE, J Biol Chem. 2004 May 28;279(22):23311-6. Epub 2004 Feb 24. PMID:14982928

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