1s9e
From Proteopedia
CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R129385
Template:ABSTRACT PUBMED 15115397
About this Structure
1S9E is a Protein complex structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
Roles of conformational and positional adaptability in structure-based design of TMC125-R165335 (etravirine) and related non-nucleoside reverse transcriptase inhibitors that are highly potent and effective against wild-type and drug-resistant HIV-1 variants., Das K, Clark AD Jr, Lewi PJ, Heeres J, De Jonge MR, Koymans LM, Vinkers HM, Daeyaert F, Ludovici DW, Kukla MJ, De Corte B, Kavash RW, Ho CY, Ye H, Lichtenstein MA, Andries K, Pauwels R, De Bethune MP, Boyer PL, Clark P, Hughes SH, Janssen PA, Arnold E, J Med Chem. 2004 May 6;47(10):2550-60. PMID:15115397
Page seeded by OCA on Mon Jul 28 21:28:36 2008
Categories: Human immunodeficiency virus 1 | Protein complex | RNA-directed DNA polymerase | Arnold, E. | Das, K. | Decorte, B. | Hughes, S H. | Janssen, P A. | Jr., A D.Clark. | Kukla, M J. | Lewi, P J. | Ludovici, D W. | Aid | Drug design | Hiv | Nnrti | Nonnucleoside inhibitor | Protein-inhibitor complex | R129385 | Reverse transcriptase | Rt
