2puq

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Template:STRUCTURE 2puq

Contents

Crystal structure of active site inhibited coagulation factor VIIA in complex with soluble tissue factor

Template:ABSTRACT PUBMED 17456045

Disease

Known disease associated with this structure: Factor VII deficiency OMIM:[227500], Myocardial infarction, decreased susceptibility to OMIM:[227500], Renal tubular dysgenesis OMIM:[106180], Angiotensin I-converting enzyme, benign serum increase OMIM:[106180], Alzheimer disease, susceptibility to OMIM:[106180], Diabetic nephropathy, susceptibility to OMIM:[106180], Myocardial infarction, susceptibility to OMIM:[106180], SARS, progression of OMIM:[106180]

About this Structure

2PUQ is a Protein complex structure of sequences from Homo sapiens. This structure supersedes the now removed PDB entry 2pmm. Full crystallographic information is available from OCA.

Reference

Engineering the substrate and inhibitor specificities of human coagulation Factor VIIa., Larsen KS, Ostergaard H, Bjelke JR, Olsen OH, Rasmussen HB, Christensen L, Kragelund BB, Stennicke HR, Biochem J. 2007 Aug 1;405(3):429-38. PMID:17456045

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