3d20

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Image:3d20.png

Template:STRUCTURE 3d20

Crystal structure of HIV-1 mutant I54V and inhibitor DARUNAVIA

Template:ABSTRACT PUBMED 18597780

About this Structure

3D20 is a Single protein structure of sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

Effect of flap mutations on structure of HIV-1 protease and inhibition by saquinavir and darunavir., Liu F, Kovalevsky AY, Tie Y, Ghosh AK, Harrison RW, Weber IT, J Mol Biol. 2008 Aug 1;381(1):102-15. Epub 2008 Jul 1. PMID:18597780

Ultra-high resolution crystal structure of HIV-1 protease mutant reveals two binding sites for clinical inhibitor TMC114., Kovalevsky AY, Liu F, Leshchenko S, Ghosh AK, Louis JM, Harrison RW, Weber IT, J Mol Biol. 2006 Oct 13;363(1):161-73. Epub 2006 Aug 4. PMID:16962136

Kinetic, stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S., Liu F, Boross PI, Wang YF, Tozser J, Louis JM, Harrison RW, Weber IT, J Mol Biol. 2005 Dec 9;354(4):789-800. Epub 2005 Oct 21. PMID:16277992

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