2b54

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Template:STRUCTURE 2b54

Human cyclin dependent kinase 2 (CKD2)complexed with DIN-232305

Template:ABSTRACT PUBMED 15537345

About this Structure

2B54 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Synthesis and biological evaluation of 1-aryl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of cyclin-dependent kinases., Markwalder JA, Arnone MR, Benfield PA, Boisclair M, Burton CR, Chang CH, Cox SS, Czerniak PM, Dean CL, Doleniak D, Grafstrom R, Harrison BA, Kaltenbach RF 3rd, Nugiel DA, Rossi KA, Sherk SR, Sisk LM, Stouten P, Trainor GL, Worland P, Seitz SP, J Med Chem. 2004 Nov 18;47(24):5894-911. PMID:15537345

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