2rgp

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Template:STRUCTURE 2rgp

Structure of EGFR in complex with hydrazone, a potent dual inhibitor

Template:ABSTRACT PUBMED 18653333

About this Structure

2RGP is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors., Xu G, Abad MC, Connolly PJ, Neeper MP, Struble GT, Springer BA, Emanuel SL, Pandey N, Gruninger RH, Adams M, Moreno-Mazza S, Fuentes-Pesquera AR, Middleton SA, Bioorg Med Chem Lett. 2008 Aug 15;18(16):4615-9. Epub 2008 Jul 10. PMID:18653333

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