1h9d

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Image:1h9d.png

Template:STRUCTURE 1h9d

Contents

AML1/CBF-BETA/DNA COMPLEX

Template:ABSTRACT PUBMED 11276260

Disease

Known disease associated with this structure: Leukemia, acute myeloid OMIM:[151385], Platelet disorder, familial, with associated myeloid malignancy OMIM:[151385], Rheumatoid arthritis, susceptibility to OMIM:[151385], Myeloid leukemia, acute, M4Eo subtype OMIM:[121360]

About this Structure

1H9D is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

The leukemia-associated AML1 (Runx1)--CBF beta complex functions as a DNA-induced molecular clamp., Bravo J, Li Z, Speck NA, Warren AJ, Nat Struct Biol. 2001 Apr;8(4):371-8. PMID:11276260

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