2qtz

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Template:STRUCTURE 2qtz

Contents

Crystal Structure of the NADP+-bound FAD-containing FNR-like Module of Human Methionine Synthase Reductase

Template:ABSTRACT PUBMED 17892308

Disease

Known disease associated with this structure: Homocystinuria-megaloblastic anemia, cbl E type OMIM:[602568], Neural tube defects, folate-sensitive, susceptibility to OMIM:[602568]

About this Structure

2QTZ is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Mechanism of coenzyme binding to human methionine synthase reductase revealed through the crystal structure of the FNR-like module and isothermal titration calorimetry., Wolthers KR, Lou X, Toogood HS, Leys D, Scrutton NS, Biochemistry. 2007 Oct 23;46(42):11833-44. Epub 2007 Sep 25. PMID:17892308

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