3ccn
From Proteopedia
Contents |
X-ray structure of c-Met with triazolopyridazine inhibitor.
Template:ABSTRACT PUBMED 18426196
Disease
Known disease associated with this structure: Hepatocellular carcinoma, childhood type OMIM:[164860], Renal cell carcinoma, papillary, familial and sporadic OMIM:[164860], Autism, suseptibility to, 9 OMIM:[164860]
About this Structure
3CCN is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Discovery and Optimization of Triazolopyridazines as Potent and Selective Inhibitors of the c-Met Kinase., Albrecht BK, Harmange JC, Bauer D, Berry L, Bode C, Boezio AA, Chen A, Choquette D, Dussault I, Fridrich C, Hirai S, Hoffman D, Larrow JF, Kaplan-Lefko P, Lin J, Lohman J, Long AM, Moriguchi J, O'Connor A, Potashman MH, Reese M, Rex K, Siegmund A, Shah K, Shimanovich R, Springer SK, Teffera Y, Yang Y, Zhang Y, Bellon SF, J Med Chem. 2008 May 22;51(10):2879-82. Epub 2008 Apr 22. PMID:18426196
Page seeded by OCA on Tue Jul 29 08:55:38 2008
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Single protein | Abrecht, B K. | Bauer, D. | Bellon, S F. | Dussault, I. | Harmange, J C. | Long, A. | Atp-binding | C-met kinase triazolopyridazine | Glycoprotein | Membrane | Nucleotide-binding | Phosphoprotein | Proto-oncogene | Receptor | Transferase | Transmembrane | Tyrosine-protein kinase
