1xkk
From Proteopedia
EGFR kinase domain complexed with a quinazoline inhibitor- GW572016
Template:ABSTRACT PUBMED 15374980
About this Structure
1XKK is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells., Wood ER, Truesdale AT, McDonald OB, Yuan D, Hassell A, Dickerson SH, Ellis B, Pennisi C, Horne E, Lackey K, Alligood KJ, Rusnak DW, Gilmer TM, Shewchuk L, Cancer Res. 2004 Sep 15;64(18):6652-9. PMID:15374980
Page seeded by OCA on Tue Jul 29 11:18:48 2008
Categories: Homo sapiens | Single protein | Transferase | Alligood, K J. | Dickerson, S H. | Ellis, B. | Gilmer, T M. | Hassell, A. | Horne, E. | Lackey, K. | McDonald, O B. | Pennisi, C. | Rusnak, D W. | Shewchuk, L M. | Truesdale, A T. | Wood, E R. | Yuan, D. | Egfr | Epidermal growth factor receptor | Kinase
