2q15
From Proteopedia
Structure of BACE complexed to compound 3a
Template:ABSTRACT PUBMED 17685503
About this Structure
2Q15 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
2-Amino-3,4-dihydroquinazolines as inhibitors of BACE-1 (beta-site APP cleaving enzyme): Use of structure based design to convert a micromolar hit into a nanomolar lead., Baxter EW, Conway KA, Kennis L, Bischoff F, Mercken MH, Winter HL, Reynolds CH, Tounge BA, Luo C, Scott MK, Huang Y, Braeken M, Pieters SM, Berthelot DJ, Masure S, Bruinzeel WD, Jordan AD, Parker MH, Boyd RE, Qu J, Alexander RS, Brenneman DE, Reitz AB, J Med Chem. 2007 Sep 6;50(18):4261-4. Epub 2007 Aug 8. PMID:17685503
Page seeded by OCA on Tue Jul 29 11:52:03 2008
