2o8e

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Image:2o8e.png

Template:STRUCTURE 2o8e

Contents

human MutSalpha (MSH2/MSH6) bound to a G T mispair, with ADP bound to MSH2 only

Template:ABSTRACT PUBMED 17531815

Disease

Known disease associated with this structure: Colorectal cancer, hereditary nonpolyposis, type 1 OMIM:[609309], Mismatch repair cancer syndrome OMIM:[609309], Muir-Torre syndrome OMIM:[609309]

About this Structure

2O8E is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Structure of the human MutSalpha DNA lesion recognition complex., Warren JJ, Pohlhaus TJ, Changela A, Iyer RR, Modrich PL, Beese LS, Mol Cell. 2007 May 25;26(4):579-92. PMID:17531815

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