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2erj

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Template:STRUCTURE 2erj

Contents

Crystal structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2

Template:ABSTRACT PUBMED 16477002

Disease

Known disease associated with this structure: Interleukin-2 receptor, alpha chain, deficiency of OMIM:[147730], Diabetes mellitus, insulin-dependent, susceptibility to, 10 OMIM:[147730], Combined immunodeficiency, X-linked, moderate OMIM:[308380], Severe combined immunodeficiency, X-linked OMIM:[308380], Severe combined immunodeficiency due to IL2 deficiency OMIM:[147680]

About this Structure

2ERJ is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor., Stauber DJ, Debler EW, Horton PA, Smith KA, Wilson IA, Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2788-93. Epub 2006 Feb 13. PMID:16477002

Page seeded by OCA on Tue Jul 29 12:44:39 2008

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