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2g8m

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Template:STRUCTURE 2g8m

Escherichia coli thymidylate synthase Y209W in complex with substrate, dUMP, and a cofactor analog, CB3717

Template:ABSTRACT PUBMED 16768437

About this Structure

2G8M is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

The role of protein dynamics in thymidylate synthase catalysis: variants of conserved 2'-deoxyuridine 5'-monophosphate (dUMP)-binding Tyr-261., Newby Z, Lee TT, Morse RJ, Liu Y, Liu L, Venkatraman P, Santi DV, Finer-Moore JS, Stroud RM, Biochemistry. 2006 Jun 20;45(24):7415-28. PMID:16768437

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