2c6d

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Template:STRUCTURE 2c6d

AURORA A KINASE ACTIVATED MUTANT (T287D) IN COMPLEX WITH ADPNP

Template:ABSTRACT PUBMED 16337122

About this Structure

2C6D is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors., Heron NM, Anderson M, Blowers DP, Breed J, Eden JM, Green S, Hill GB, Johnson T, Jung FH, McMiken HH, Mortlock AA, Pannifer AD, Pauptit RA, Pink J, Roberts NJ, Rowsell S, Bioorg Med Chem Lett. 2006 Mar 1;16(5):1320-3. Epub 2005 Dec 5. PMID:16337122

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