3g42

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Image:3g42.jpg

Template:STRUCTURE 3g42

Crystal Structure of TACE with Tryptophan Sulfonamide Derivative Inhibitor

Template:ABSTRACT PUBMED 19410464

About this Structure

3G42 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Park K, Gopalsamy A, Aplasca A, Ellingboe JW, Xu W, Zhang Y, Levin JI. Synthesis and activity of tryptophan sulfonamide derivatives as novel non-hydroxamate TNF-alpha converting enzyme (TACE) inhibitors. Bioorg Med Chem. 2009 Jun 1;17(11):3857-65. Epub 2009 Apr 22. PMID:19410464 doi:10.1016/j.bmc.2009.04.033

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