User:Tilman Schirmer/Sandbox 201

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PleD

Contents 1 Intro 2 Domain structure 3 Protomer 4 Substrate binding site 5 Allosteric product binding site 5.1 C-di-GMP 5.2 Primary inhibition site (Ip) 5.3 Secondary inhibition site (Is) 5.4 Primary and secondary inhibition sites 6 Two conformations 7 Non-activated conformation 8 Activated conformation

Intro

Domain structure

Protomer

spinqualitylabelsall models Diguanylate cyclase PleD (1w25) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

: , ,

Substrate binding site

spinqualitylabelsall models 2v0n Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Allosteric product binding site

spinqualitylabelsall models Allosteric product binding site Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

C-di-GMP

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Primary inhibition site (Ip)

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Secondary inhibition site (Is)

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Primary and secondary inhibition sites

Two conformations

spinqualitylabelsall models non-activated (1w25) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

spinqualitylabelsall models activated (BeF3- modified; 2v0n) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Non-activated conformation

1w25

spinqualitylabelsall models 1w25 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

: , ,

Activated conformation

2v0n

spinqualitylabelsall models 2v0n Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image