C-di-GMP

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Cyclic di-GMP, (bis-(3'-5') cyclic diguanylic acid)

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C-di-GMP is a second messenger that mediates the regulation of cell-surface associated traits in bacteria.

is a cyclic dinucleotide with a 12-membered macro-cycle composed of the the phosphate and ribose moieties. It tends to associate to form with intercalated, stacked bases.

Several protein structures involved in c-di-GMP signaling have been determined (reviewed in User:Tilman_Schirmer/Sandbox_200).