3eax

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Image:3eax.jpg

Template:STRUCTURE 3eax

Crystal structure PTP1B complex with small molecule compound LZP-6

Template:ABSTRACT PUBMED 19012396

About this Structure

3EAX is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Liu S, Zeng LF, Wu L, Yu X, Xue T, Gunawan AM, Long YQ, Zhang ZY. Targeting inactive enzyme conformation: aryl diketoacid derivatives as a new class of PTP1B inhibitors. J Am Chem Soc. 2008 Dec 17;130(50):17075-84. PMID:19012396 doi:10.1021/ja8068177

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