2wcx

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Image:2wcx.jpg

Template:STRUCTURE 2wcx

CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN COMPLEX WITH THIENOPYRROLE-BASED FINGER-LOOP INHIBITORS

About this Structure

2WCX is a 1 chain structure of sequence from Hepatitis c virus. Full crystallographic information is available from OCA.

Reference

  • Di Marco S, Volpari C, Tomei L, Altamura S, Harper S, Narjes F, Koch U, Rowley M, De Francesco R, Migliaccio G, Carfi A. Interdomain communication in hepatitis C virus polymerase abolished by small molecule inhibitors bound to a novel allosteric site. J Biol Chem. 2005 Aug 19;280(33):29765-70. Epub 2005 Jun 13. PMID:15955819 doi:http://dx.doi.org/10.1074/jbc.M505423200

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