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descDate Name User Size Description
19:09, 27 April 2025 Glycerol_Ligand_in_Ferritin_3KX9.png (file) Alexander Grayzel 25 KB (Gycerol in ferritin.)
17:12, 27 April 2025 Minibinders_RBD.jpg (file) Lilly Hiester 58 KB  
15:41, 27 April 2025 3HO4_overlap_with_1n8o.png (file) Cameron Snelbaker 40 KB (3H04 overlap with 1n8o)
15:40, 27 April 2025 3H04_overlap_with_1pfp.png (file) Cameron Snelbaker 43 KB (SPRITE overlap of 3H04 with 1pfp)
15:27, 27 April 2025 3H04_overlap_with_1zoi.png (file) Cameron Snelbaker 45 KB  
14:27, 27 April 2025 BRD_Mechanism.jpg (file) James Lignos 111 KB (Bromodomains are epigenetic "readers" that bind to acetylated lysines on N-terminal histone tails. Histone acetylation is a post translational modification that is associated with regions of chromatin that are primed for transcription. Bromodomains bind t)
01:17, 27 April 2025 TableDali.jpg (file) Emma Caszatt 64 KB  
01:15, 27 April 2025 FinalConc.jpg (file) Emma Caszatt 25 KB  
01:15, 27 April 2025 FinalConc.jpeg (file) Emma Caszatt 25 KB  
01:12, 27 April 2025 TableDali.jpeg (file) Emma Caszatt 64 KB  
01:10, 27 April 2025 SwissDock1.jpg (file) Emma Caszatt 35 KB  
00:45, 27 April 2025 Screen_Shot_2025-04-26_at_8.44.28_PM.png (file) Maria. Brzezinski 58 KB (Chimera image of 3B7F and 1XNY_C00)
00:43, 27 April 2025 Assay2.jpg (file) Emma Caszatt 40 KB  
00:42, 27 April 2025 Assay.jpg (file) Emma Caszatt 39 KB  
00:41, 27 April 2025 FinalConc.png (file) Emma Caszatt 8 KB  
00:40, 27 April 2025 StandardCurve.jpg (file) Emma Caszatt 40 KB  
00:36, 27 April 2025 SwissDock1.png (file) Emma Caszatt 116 KB  
00:32, 27 April 2025 BLAST.jpg (file) Emma Caszatt 29 KB  
00:31, 27 April 2025 TableDali.png (file) Emma Caszatt 32 KB  
00:26, 27 April 2025 Chimera.jpg (file) Emma Caszatt 45 KB  
00:24, 27 April 2025 SPRITE.jpg (file) Emma Caszatt 6 KB  
23:02, 26 April 2025 ComplexLabeled.pse (file) Peyton Jenkins 9.96 MB  
18:44, 26 April 2025 AF-W8VY28-F1-model_v4.pdb (file) Anders Lewisesquerre 106 KB  
16:02, 26 April 2025 PfBDP1_inhibition.png (file) James Lignos 212 KB (Cartoon depiction of drug based rationale for targeting the bromodomain of PfBDP1 to block its interaction with chromatin ligands at the promoters of genes implicated in host cell invasion as a strategy to combat malaria.)
15:59, 26 April 2025 PfBDP1_inhibition.pdf (file) James Lignos 186 KB (Cartoon depiction of drug based rationale for targeting the bromodomain of PfBDP1 to block its interaction with chromatin ligands at the promoters of genes implicated in host cell invasion as a strategy to combat malaria.)
15:54, 26 April 2025 PfBDP1_Inhibition_Schematic.png (file) James Lignos 212 KB (Cartoon depiction of drug based rationale for targeting the bromodomain of PfBDP1 to block its interaction with acetylated chromatin ligands at the promoters of genes implicated in host cell invasion as a strategy to combat malaria.)
15:54, 26 April 2025 PfBDP1_Inhibition_schematic.png (file) James Lignos 212 KB (Cartoon depiction of drug based rationale for targeting the bromodomain of PfBDP1 to block its interaction with acetylated chromatin ligands at the promoters of genes implicated in host cell invasion as a strategy to combat malaria.)
15:53, 26 April 2025 Screenshot_2025-04-26_at_11.44.58 AM.png (file) James Lignos 212 KB (Cartoon depiction of drug based rationale for targeting the bromodomain of PfBDP1 to block its interaction with acetylated chromatin ligands at the promoters of genes implicated in host cell invasion as a strategy to combat malaria.)
15:50, 26 April 2025 Screenshot_2025-04-26_at_11.44.58 AM.pdf (file) James Lignos 186 KB (Cartoon depiction of drug based rationale for targeting the PfBDP1 bromdodomain to block the interaction between chromatin ligands and PfBDP1 at the promoters of genes implicated in host cell invasion as a strategy to combat malaria.)
14:45, 26 April 2025 Kd_table.png (file) Carson Powers 40 KB (Table 1. Dissociation constants (Kd) for SARS-CoV-2 spike RBD binding to ACE2 and engineered minibinders, measured by biolayer interferometry to compare affinities for the spike protein. )
14:03, 26 April 2025 Spike_infection_cycle.png (file) Carson Powers 356 KB (SARS-CoV-2 infection cycle: the viral spike protein (cyan) binds to the ACE2 receptor (magenta) on the cell surface, triggering endocytosis and ACE2 down-regulation, release of viral RNA into the cytosol, translation of the viral polymerase and genome rep)
18:26, 25 April 2025 4Q7QpfamLipases.png (file) Neil Singer Divins 107 KB (Pfam stack similarities between 4q7q and various enzymes)
18:25, 25 April 2025 4Q7QOrigin.png (file) Neil Singer Divins 364 KB (a)
18:24, 25 April 2025 4Q7QABSequence.png (file) Neil Singer Divins 189 KB (Primary Sequence of both 4Q7Q chains)
18:23, 25 April 2025 4Q7QLipasesConserv.png (file) Neil Singer Divins 112 KB (Conserved Sequences between 4Q7Q and Lipases)
18:22, 25 April 2025 4Q7QLipasesSecondary.png (file) Neil Singer Divins 94 KB (Secondary Structure Overlap between 4Q7Q and Lipases)
18:21, 25 April 2025 DecanoateDocking.png (file) Neil Singer Divins 336 KB (SwissDock Results 4Q7Q + Decanoate)
18:20, 25 April 2025 ThioesteraseIStructure.png (file) Neil Singer Divins 93 KB (a)
18:16, 25 April 2025 4Q7QSecondaryEsterases.png (file) Neil Singer Divins 59 KB (Secondary Structure Alignments between 4Q7Q and Esterases)
18:16, 25 April 2025 4Q7QDockingEnergies.png (file) Neil Singer Divins 14 KB (SwissDock Results from 4Q7Q analysis)
18:15, 25 April 2025 4Q7QEsteraseConserv.png (file) Neil Singer Divins 59 KB (Conserved Sequences between 4Q7Q and various esterases.)
18:11, 25 April 2025 4Q7QPAFASPRITE.png (file) Neil Singer Divins 51 KB (Sprite Alignment between 4Q7Q Motif and Platelet-Activating Factor Acetylhyd Motif)
18:04, 25 April 2025 4Q7QAChain.png (file) Neil Singer Divins 250 KB (CHIMERA-Generated 4Q7QAChain Cartoon Model)
17:29, 25 April 2025 PONDR.jpg (file) Marcos Ngo 39 KB  
14:05, 25 April 2025 PlasticImage.png (file) Hayden Vissing 1.15 MB  
14:05, 25 April 2025 2D.png (file) Hayden Vissing 97 KB  
19:03, 24 April 2025 DAdienestructure_Large.jpeg (file) Katherine Thuma 51 KB  
18:49, 24 April 2025 OGDAmech.jpeg (file) Katherine Thuma 54 KB  
18:33, 24 April 2025 DAstereoselectivity.png (file) Katherine Thuma 74 KB  
15:32, 24 April 2025 Trash.pse (file) Peyton Jenkins 543 KB  

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