This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2wot
From Proteopedia
ALK5 IN COMPLEX WITH 4-((5,6-DIMETHYL-2-(2-PYRIDYL)-3-PYRIDYL)OXY)-N-(3,4,5-TRIMETHOXYPHENYL)PYRIDIN-2-AMINE
Template:ABSTRACT PUBMED 19736928
About this Structure
2WOT is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Goldberg FW, Ward RA, Powell SJ, Debreczeni JE, Norman RA, Roberts NJ, Dishington AP, Gingell HJ, Wickson KF, Roberts AL. Rapid Generation of a High Quality Lead for Transforming Growth Factor-beta (TGF-beta) Type I Receptor (ALK5) (dagger). J Med Chem. 2009 Sep 8. PMID:19736928 doi:10.1021/jm900807w
Page seeded by OCA on Wed Sep 23 08:49:17 2009
Categories: Homo sapiens | Receptor protein serine/threonine kinase | Debreczeni, J E. | Dishington, A P. | Finlay, R. | Gingell, H J. | Goldberg, F W. | Norman, R A. | Powell, S J. | Roberts, A L. | Roberts, N J. | Ward, R A. | Wickson, K. | Alk5 | Aortic aneurysm | Atp-binding | Craniosynostosis | Disease mutation | Disulfide bond | Glycoprotein | Kinase | Kinase inhibitor | Manganese | Membrane | Metal-binding | Nucleotide-binding | Phosphoprotein | Receptor | Serine/threonine-protein kinase | Tgf beta type i receptor | Transferase | Transmembrane
