1qbv

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Image:1qbv.png

Template:STRUCTURE 1qbv

CRYSTAL STRUCTURE OF THROMBIN COMPLEXED WITH AN GUANIDINE-MIMETIC INHIBITOR

Template:ABSTRACT PUBMED 9622548

About this Structure

1QBV is a 3 chains structure of sequences from Hirudinaria manillensis and Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bone R, Lu T, Illig CR, Soll RM, Spurlino JC. Structural analysis of thrombin complexed with potent inhibitors incorporating a phenyl group as a peptide mimetic and aminopyridines as guanidine substitutes. J Med Chem. 1998 Jun 4;41(12):2068-75. PMID:9622548 doi:10.1021/jm970796l

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