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3hp2
From Proteopedia
Crystal Structure of Human p38alpha complexed with a pyridinone compound
Template:ABSTRACT PUBMED 19751974
About this Structure
3HP2 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Selness SR, Devraj RV, Monahan JB, Boehm TL, Walker JK, Devadas B, Durley RC, Kurumbail R, Shieh H, Xing L, Hepperle M, Rucker PV, Jerome KD, Benson AG, Marrufo LD, Madsen HM, Hitchcock J, Owen TJ, Christie L, Promo MA, Hickory BS, Alvira E, Naing W, Blevis-Bal R. Discovery of N-substituted pyridinones as potent and selective inhibitors of p38 kinase. Bioorg Med Chem Lett. 2009 Oct 15;19(20):5851-6. Epub 2009 Aug 27. PMID:19751974 doi:10.1016/j.bmcl.2009.08.082
Page seeded by OCA on Wed Sep 30 09:11:25 2009
Categories: Homo sapiens | Mitogen-activated protein kinase | Kurumbail, R G. | Shieh, H S. | Stegeman, R A. | Williams, J M. | Alternative splicing | Atp site and distal site | Atp-binding | Cytoplasm | Kinase | Nucleotide-binding | Nucleus | Peptide flip | Phosphoprotein | Polymorphism | Serine/threonine-protein kinase | Transferase | Two binding site | Two ligand | Two lobe
