3ffk

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Image:3ffk.jpg

Template:STRUCTURE 3ffk

Contents

Crystal structure of human Gelsolin domains G1-G3 bound to Actin

Template:ABSTRACT PUBMED 19666512

Disease

Known disease associated with this structure: Amyloidosis, Finnish type OMIM:[137350]

About this Structure

3FFK is a 4 chains structure of sequences from Homo sapiens and Oryctolagus cuniculus. Full crystallographic information is available from OCA.

Reference

  • Nag S, Ma Q, Wang H, Chumnarnsilpa S, Lee WL, Larsson M, Kannan B, Hernandez-Valladares M, Burtnick LD, Robinson RC. Ca2+ binding by domain 2 plays a critical role in the activation and stabilization of gelsolin. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13713-8. Epub 2009 Aug 4. PMID:19666512

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