1h1k

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Image:1h1k.gif

1h1k, resolution 10.Å

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THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA

Overview

Double-stranded RNA (dsRNA) viruses conceal their genome from the host to, avoid triggering unfavorable cellular responses. The crystal structure of, the core of one such virus, bluetongue virus, reveals an outer surface, festooned with dsRNA. This may represent a deliberate strategy to, sequester dsRNA released from damaged particles to prevent host cell, shutoff.

About this Structure

1H1K is a Single protein structure of sequence from Bluetongue virus. Full crystallographic information is available from OCA.

Reference

The core of bluetongue virus binds double-stranded RNA., Diprose JM, Grimes JM, Sutton GC, Burroughs JN, Meyer A, Maan S, Mertens PP, Stuart DI, J Virol. 2002 Sep;76(18):9533-6. PMID:12186935

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