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2kj2

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Image:2kj2.jpg

Template:STRUCTURE 2kj2

All parallel G-quadruplex from the promoter sequence of the c-kit oncogene

Template:ABSTRACT PUBMED 19705869

About this Structure

2KJ2 is a 1 chain structure. Full experimental information is available from OCA.

Reference

  • Hsu ST, Varnai P, Bugaut A, Reszka AP, Neidle S, Balasubramanian S. A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics. J Am Chem Soc. 2009 Sep 23;131(37):13399-409. PMID:19705869 doi:10.1021/ja904007p
  • Fernando H, Reszka AP, Huppert J, Ladame S, Rankin S, Venkitaraman AR, Neidle S, Balasubramanian S. A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene. Biochemistry. 2006 Jun 27;45(25):7854-60. PMID:16784237 doi:10.1021/bi0601510

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