This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2v4h
From Proteopedia
NEMO CC2-LZ DOMAIN - 1D5 DARPIN COMPLEX
Template:ABSTRACT PUBMED 19854204
About this Structure
2V4H is a 4 chains structure of sequences from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Grubisha O, Kaminska M, Duquerroy S, Fontan E, Cordier F, Haouz A, Raynal B, Chiaravalli J, Delepierre M, Israel A, Veron M, Agou F. DARPin-assisted crystallography of the CC2-LZ domain of NEMO reveals a coupling between dimerization and ubiquitin binding. J Mol Biol. 2010 Jan 8;395(1):89-104. Epub 2009 Oct 23. PMID:19854204 doi:10.1016/j.jmb.2009.10.018
- Wyler E, Kaminska M, Coic YM, Baleux F, Veron M, Agou F. Inhibition of NF-kappaB activation with designed ankyrin-repeat proteins targeting the ubiquitin-binding/oligomerization domain of NEMO. Protein Sci. 2007 Sep;16(9):2013-22. PMID:17766391 doi:16/9/2013
Page seeded by OCA on Wed Nov 4 10:49:43 2009
Categories: Mus musculus | Agou, F. | Cordier, F. | Delepierre, M. | Duquerroy, S. | Grubisha, O. | Haouz, A. | Veron, M. | Coiled coil | Cytoplasm | Metal-binding | Nemo - ikk gamma - nfkb pathway - darpin | Nucleus | Phosphoprotein | Transcription | Transcription regulation | Ubl conjugation | Zinc | Zinc-finger
