3bxn

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Image:3bxn.png

Template:STRUCTURE 3bxn

Contents

The high resolution crystal structure of HLA-B*1402 complexed with a Cathepsin A signal sequence peptide, pCatA

Template:ABSTRACT PUBMED 19617632

Disease

Known disease associated with this structure: Abacavir hypersensitivity, susceptibility to OMIM:[142830], Spondyloarthropathy, susceptibility to, 1 OMIM:[142830], Stevens-Johnson syndrome, carbamazepine-induced, susceptibility to OMIM:[142830], Hypoproteinemia, hypercatabolic OMIM:[109700]

About this Structure

3BXN is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Kumar P, Vahedi-Faridi A, Saenger W, Merino E, Lopez de Castro JA, Uchanska-Ziegler B, Ziegler A. Structural basis for T cell alloreactivity among three HLA-B14 and HLA-B27 antigens. J Biol Chem. 2009 Oct 23;284(43):29784-97. Epub 2009 Jul 18. PMID:19617632 doi:10.1074/jbc.M109.038497

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