2who
From Proteopedia
CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE FROM 1B GENOTYPE IN COMPLEX WITH A NON-NUCLEOSIDE INHIBITOR
Template:ABSTRACT PUBMED 19877603
About this Structure
2WHO is a 2 chains structure of sequences from Hepatitis c virus. Full crystallographic information is available from OCA.
Reference
- Ontoria JM, Rydberg EH, Di Marco S, Tomei L, Attenni B, Malancona S, Martin Hernando JI, Gennari N, Koch U, Narjes F, Rowley M, Summa V, Carroll SS, Olsen DB, De Francesco R, Altamura S, Migliaccio G, Carfi A. Identification and Biological Evaluation of a Series of 1H-Benzo[de]isoquinoline-1,3(2H)-diones as Hepatitis C Virus NS5B Polymerase Inhibitors (double dagger). J Med Chem. 2009 Aug 27;52(16):5217-27. PMID:19877603 doi:10.1021/jm900517t
Page seeded by OCA on Wed Nov 11 22:48:11 2009
Categories: Hepatitis c virus | RNA-directed RNA polymerase | Marco, S Di. | Allosteric inhibitor | Atp-binding | Endoplasmic reticulum | Envelope protein | Genotype 1b | Hcv | Helicase | Hydrolase | Membrane | Metal-binding | Nni | Non nucleoside inhibitor | Ns5b | Nucleotide-binding | Polymerase | Rna replication | Rna-binding | Rna-dependent rna polymerase | Rna-directed rna polymerase | Transferase | Transmembrane | Viral protein
