3imj

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Image:3imj.png

Template:STRUCTURE 3imj

Crystal Structure of the Grb2 SH2 Domain in Complex with a Cyclopropyl-constrained Ac-pTyr-Ile-Asn-NH2 Tripeptide Mimic

Template:ABSTRACT PUBMED 19886660

About this Structure

3IMJ is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Delorbe JE, Clements JH, Teresk MG, Benfield AP, Plake HR, Millspaugh LE, Martin SF. Thermodynamic and Structural Effects of Conformational Constraints in Protein-Ligand Interactions. Entropic Paradoxy Associated with Ligand Preorganization. J Am Chem Soc. 2009 Nov 3. PMID:19886660 doi:10.1021/ja904698q

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