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3gky
From Proteopedia
The Structural Basis of an ER Stress-Associated Bottleneck in a Protein Folding Landscape
About this Structure
3GKY is a 4 chains structure. Full crystallographic information is available from OCA.
Reference
- Liu M, Wan ZL, Chu YC, Aladdin H, Klaproth B, Choquette M, Hua QX, Mackin RB, Rao JS, De Meyts P, Katsoyannis PG, Arvan P, Weiss MA. Crystal structure of a "nonfoldable" insulin: impaired folding efficiency despite native activity. J Biol Chem. 2009 Dec 11;284(50):35259-72. Epub 2009 Oct 22. PMID:19850922 doi:10.1074/jbc.M109.046888
Page seeded by OCA on Wed Dec 23 09:00:55 2009
Categories: Alddin, H. | Chu, Y C. | Klaproth, B | Liu, M. | Wan, Z L. | Weiss, M A. | Carbohydrate metabolism | Cleavage on pair of basic residue | Diabetes mellitus | Disease mutation | Disulfide bond | Er stress-associated | Glucose metabolism | Hormone | Pharmaceutical | Protein folding | Secreted | Tr transition receptor binding
