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3jsw

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Revision as of 07:04, 23 December 2009 by OCA (Talk | contribs)
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Image:3jsw.png

Template:STRUCTURE 3jsw

Human PDE9 in complex with selective inhibitor

About this Structure

3JSW is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Verhoest PR, Proulx-Lafrance C, Corman M, Chenard L, Helal CJ, Hou X, Kleiman R, Liu S, Marr E, Menniti FS, Schmidt CJ, Vanase-Frawley M, Schmidt AW, Williams RD, Nelson FR, Fonseca KR, Liras S. Identification of a brain penetrant PDE9A inhibitor utilizing prospective design and chemical enablement as a rapid lead optimization strategy. J Med Chem. 2009 Dec 24;52(24):7946-9. PMID:19919087 doi:10.1021/jm9015334

Page seeded by OCA on Wed Dec 23 09:04:17 2009

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