3iad

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Image:3iad.jpg

Template:STRUCTURE 3iad

Crystal structure of human phosphodiesterase 4D with bound allosteric modulator

Template:ABSTRACT PUBMED 20037581

About this Structure

3IAD is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Burgin AB, Magnusson OT, Singh J, Witte P, Staker BL, Bjornsson JM, Thorsteinsdottir M, Hrafnsdottir S, Hagen T, Kiselyov AS, Stewart LJ, Gurney ME. Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety. Nat Biotechnol. 2010 Jan;28(1):63-70. Epub 2009 Dec 27. PMID:20037581 doi:10.1038/nbt.1598

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