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Syn and Anti Configurations of Nucleosides and Nucleotides
Detailed description of nucleosides and nucleotides.
Purine Nucleosides
Observe that the adenine ring of adenosine is nearly perpendicular to the furanose ring and that a (colored green) connects adenine to ribofuranose. Groups on the ribofuranose, such as the hydrogen on the 2' carbon sterically hinder the rotation of the adenine about the glycosidic bond. This lack of ability to rotate results in two possible configurations. The which you have been viewing. shows the and when displayed in spacefill one can see that the
hydrogen of the 2' carbon hinders the rotation of the purine ring about the glycosidic bond.
