3i4b

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Image:3i4b.jpg

Template:STRUCTURE 3i4b

Crystal structure of GSK3b in complex with a pyrimidylpyrrole inhibitor

Template:ABSTRACT PUBMED 19827834

About this Structure

3I4B is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Aronov AM, Tang Q, Martinez-Botella G, Bemis GW, Cao J, Chen G, Ewing NP, Ford PJ, Germann UA, Green J, Hale MR, Jacobs M, Janetka JW, Maltais F, Markland W, Namchuk MN, Nanthakumar S, Poondru S, Straub J, ter Haar E, Xie X. Structure-guided design of potent and selective pyrimidylpyrrole inhibitors of extracellular signal-regulated kinase (ERK) using conformational control. J Med Chem. 2009 Oct 22;52(20):6362-8. PMID:19827834 doi:10.1021/jm900630q

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